Aicardi Syndrome

General

• Only in girls
• Chorioretinopathy
• Other eye problems

Airway

• Microcephaly
• Possible cleft lip/palate

Respiratory

• Scoliosis
• Abnl ribs
• Aspiration/frequent pneumonia

Gastrointestinal

• Hiatal hernia
• Reflux risk

Endocrine

• Precocious puberty

Neurological

• Infantile spasms
• Agenesis of corpus callosum
• Microcephaly
• Severe mental retardation
• Hypotonia
• CNS tumors

Musculoskeletal

• Kyphoscoliosis
• Abnl vertebrae

Considerations

• Aspiration risk
• Respiratory difficulties
• Seizure medications may affect drug metabolism